ALLN-177, oral enzyme therapy for hyperoxaluria
نویسندگان
چکیده
منابع مشابه
Oral manifestations of hyperoxaluria.
Primary hyperoxaluria is a rare, inherited autosomal recessive disease caused by defects in the metabolism of glyoxylate. Oral manifestations of hyperoxaluria are rare. However, bone and tooth resorption may be the result of chronic inflammation and the presence of osteoclastic cells surrounding the oxalate crystal deposit. A deposit of calcium oxalate in the periodontium was identified in a pa...
متن کاملassessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
چکیده ندارد.
15 صفحه اولHyperoxaluria in urolithiasis and Cystone Therapy
Twenty-seven patients with urolithiasis and twenty-three normal subjects comprised this study. They were kept on an oxalate-free diet for 48 hr prior to and during urine collection to rule out any dietary influence on oxaluria. 24-hr urine samples were collected for oxalic acid estimation. After this all the patients received Cystone, 2 tabs. t.i.d. for 8 weeks. The above procedures were repeat...
متن کاملPrimary Hyperoxaluria
Primary hyperoxalurias are rare recessive inherited inborn errors of glyoxylate metabolism. They are responsible for progressive renal involvement, which further lead to systemic oxalate deposition, which can even occur in infants. Primary hyperoxaluria type 1 is the most common form in Europe and is due to alanine-glyoxylate aminostransferase deficiency, a hepatic peroxisomal pyridoxin-depende...
متن کاملPlant-based oral delivery of β-glucocerebrosidase as an enzyme replacement therapy for Gaucher's disease.
Gaucher's disease (GD), a lysosomal storage disorder caused by mutations in the gene encoding glucocerebrosidase (GCD), is currently treated by enzyme replacement therapy (ERT) using recombinant GCD that is administered intravenously every 2 weeks. However, intravenous administration includes discomfort or pain and might cause local and systemic infections that may lead to low patient complianc...
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ژورنال
عنوان ژورنال: International Urology and Nephrology
سال: 2019
ISSN: 0301-1623,1573-2584
DOI: 10.1007/s11255-019-02098-1